Program
MSE3 | Woodward 3; 10:15 am - 12:15 pm, July 29 |
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Title | Towards quantitative integrated oncology-why 1+1 is greater than 2 - Part I |
Organizers | Kasia Rejniak |
H. Lee Moffitt Cancer Center and Research Institute | |
Heiko Enderling | |
Tufts University School of Medicine | |
Abstract | This minisymposium is intended to show current progress in integrating mathematical and computational models of tumor formation, progression and treatment with experimental and clinical data. We will present a variety of problems in cancer research, and bring together pairs of researchers that approach these problems from the experimental or clinical point of view as well as using mathematical or computational modeling techniques. This minisymposium aims to showcase and stimulate collaborative and integrative research, addressing different topics including tissue architecture and tumor formation, cancer cell and tumor-microenvironment interactions, and cell metabolism and interstitial acidosis in solid tumors. We would like to allocate 45 minutes for each presentation given jointly by both collaborators and 15 minutes for questions and answers for both speakers. Each talk will be split by a collaborating pair to cover an introduction to the biology of a particular tumor, a presentation of experimental results to understand the systems under consideration, followed by a presentation of a theoretical model aimed to improve understanding of the biological system dynamics and a join discussion on modeling challenges and future directions. |
Speaker 1 | Lisa McCawley |
Vanderbilt University Medical School | |
An integrative approach in modeling bio-mechanics of epithelial cancer initiation. Experimental view | |
Speaker 2 | Kasia Rejniak |
H. Lee Moffitt Cancer Center & Research Institute | |
An integrative approach in modeling bio-mechanics of epithelial cancer initiation. Bio-mechanical view | |
Speaker 3 | Afshin Beheshti |
Tufts University School of Medicine | |
The induction of DNA double-strand breaks in bystander stromal cells by cancer cells, a biological perspective | |
Speaker 4 | Heiko Enderling |
Tufts University School of Medicine | |
The induction of DNA double-strand breaks in bystander stromal cells by cancer cells, a computational perspective |
Link to Part II - MSG3
-- Minisymposium talks are scheduled for 30 min each, including time for questions.