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International Conference on Mathematical Biology and

Annual Meeting of The Society for Mathematical Biology,

July 27-30, 2009

University of British Columbia, Vancouver

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Program

MSE3Woodward 3;   10:15 am - 12:15 pm, July 29
TitleTowards quantitative integrated oncology-why 1+1 is greater than 2 - Part I
OrganizersKasia Rejniak
H. Lee Moffitt Cancer Center and Research Institute
Heiko Enderling
Tufts University School of Medicine
AbstractThis minisymposium is intended to show current progress in integrating mathematical and computational models of tumor formation, progression and treatment with experimental and clinical data. We will present a variety of problems in cancer research, and bring together pairs of researchers that approach these problems from the experimental or clinical point of view as well as using mathematical or computational modeling techniques. This minisymposium aims to showcase and stimulate collaborative and integrative research, addressing different topics including tissue architecture and tumor formation, cancer cell and tumor-microenvironment interactions, and cell metabolism and interstitial acidosis in solid tumors.

We would like to allocate 45 minutes for each presentation given jointly by both collaborators and 15 minutes for questions and answers for both speakers. Each talk will be split by a collaborating pair to cover an introduction to the biology of a particular tumor, a presentation of experimental results to understand the systems under consideration, followed by a presentation of a theoretical model aimed to improve understanding of the biological system dynamics and a join discussion on modeling challenges and future directions.
Speaker 1Lisa McCawley
Vanderbilt University Medical School
An integrative approach in modeling bio-mechanics of epithelial cancer initiation. Experimental view
Speaker 2Kasia Rejniak
H. Lee Moffitt Cancer Center & Research Institute
An integrative approach in modeling bio-mechanics of epithelial cancer initiation. Bio-mechanical view
Speaker 3Afshin Beheshti
Tufts University School of Medicine
The induction of DNA double-strand breaks in bystander stromal cells by cancer cells, a biological perspective
Speaker 4Heiko Enderling
Tufts University School of Medicine
The induction of DNA double-strand breaks in bystander stromal cells by cancer cells, a computational perspective

-- Minisymposium talks are scheduled for 30 min each, including time for questions.