Program
| MSA1 | Woodward 1; 10:15 am - 12:15 pm, July 27 |
|---|---|
| Title | Case studies of reactions at the cell membrane: modeling and experiment. - Part I |
| Organizer | Omer Dushek |
| Oxford University | |
| Abstract | Reactions at the cell membrane are frequent because they allow cells interact with the external environment. Critical to the study of such processes are mathematical models that are accurate, efficient, and are able to relate experimentally measured parameter (often ensemble quantities) to model parameters (often between individual reactants). The aim of this mini-symposium is to bring together experimentalists and mathematical modelers to present case studies of reactions involving the cell membrane. Topics covered include: signal transduction across the membrane, recruitment of cytosolic proteins to the membrane, and the mobility and aggregation of membrane proteins. |
| Speaker 1 | Omer Dushek |
| Sir William Dunn School of Pathology, Oxford University | |
| A role for localized rebinding in rapid and reliable T cell responses | |
| Speaker 2 | Jonathan Cooper |
| Fred Hutchinson Cancer Research Center | |
| A mechanism for transmembrane signal transduction by Src kinases | |
| Speaker 3 | Ambarish Nag |
| Los Alamos National Laboratory | |
| Aggregation of membrane proteins by cytosolic cross-linkers: Modeling of LAT aggregation mediated by cytosolic complex of Grb2 and SOS1 proteins | |
| Speaker 4 | Christopher Cairo |
| University of Alberta | |
| Diffusion of adhesion molecules in the T cell membrane and the role of lateral mobility in signaling mechanisms |
Link to Part II - MSB1
-- Minisymposium talks are scheduled for 30 min each, including time for questions.