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International Conference on Mathematical Biology and

Annual Meeting of The Society for Mathematical Biology,

July 27-30, 2009

University of British Columbia, Vancouver

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Program

MSD3c
Gerda de Vries
University of Alberta
Title Quantitative Analysis of Single Particle Tracking Experiments
Abstract A commonly used experimental technique to study the movement of biomolecules is Single Particle Tracking (SPT). SPT involves tagging biomolecules (such as proteins) with a fluorescent label and observing and
recording their trajectories over time. A diffusion coefficient describing the movement of the biomolecules then can be extracted from the data from mean square displacement calculations. The method of data collection from individual biomolecules is analogous to that from individual animals. Ecologists regularly quantify movement from observation of animals moving in the field, using the concepts of net squared displacement and residence index. We (1) explore the quantitative methods used in ecology to
characterize the movement of animals from tracking data, and (2) investigate the possibility of adapting these methods to characterize the movement of biomolecules.
LocationWoodward 3