Abstract | GA is a hormone that is thought to regulate cell growth by affecting the cell-wall remodelling enzymes. In this talk, I will present a multiscale model that describes the role of GA in the root elongation zone. The model includes: (i) diffusion and dilution of GA, (ii) a genetic regulatory network that details how GA affects the DELLA proteins, (iii) a description of how the DELLA proteins influence the cell-wall remodelling enzymes, which in turn affect the cell-wall material properties, and finally (iv) a cell growth model derived by Rosemary Dyson (presented earlier in the minisymposium). Using the model, we can understand how these processes may interact to produce the growth patterns seen in wild type and mutant plants. I will also discuss the work of my experimental collaborators, who are currently collecting data to test the model's predictions. |