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International Conference on Mathematical Biology and

Annual Meeting of The Society for Mathematical Biology,

July 27-30, 2009

University of British Columbia, Vancouver

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Program

Poster PS35B
Taruna Singh
Case Western Reserve University
Title Mathematical Analysis of Cognitive Output of Alzheimer's Disease
Abstract Statistical measures of graph and network theory have been shown to correlate with a group’s level of dementia. This study follows this idea by calculating the Euclidean Distance and Maximum Difference Distances between Normal, Mild Cognitive Impairment, and Alzheimer's Disease, for both Animal and Vegetable Tests of Category Fluency. Both measures of distance show that Transition Matrices consisting of connections between the ten most common nodes preserve differences in cognitive output. An exponential decay in patient response rate (responses per fifteen second bins) encourages further study to determine if Markov properties are present in patient responses. We are currently pursuing the idea of preferential attachment as it relates to normal and Alzheimer’s patients.
CoauthorsTaruna Singh, David Meyer, Jason Messer, Peter J Thomas, Wojbor A Woyczynski, Alan J Lerner
LocationWoodward Lobby (Wednesday-Thursday)